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Isolation of a DNA adduct (04/16/1976)
Purpose/Intro: "Background: over the past 4 months, Bill Busby and Bob Croy have established an hydrolysis method and an HPLC separation for an "adduct" in several in vitro incubation samples. I am now going to isolate enough material for physico-chemical studies."
Results/Conclusion: All hydrolysates had a peak at tR = 20 min (Peak 1). This could be the adduct.
Notes: DNA was hydrolyzed enzymatically (DNAase I and nuclease P1).
Links:
PDF: See this in the notebook!
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